Clinical Trials & Research

One in five multi-drug resistant (MDR) tuberculosis (TB) cases in children under the age of 15 could be averted every year by household contact management, according to a new modeling study published in The Lancet Global Health. The research from the London School of Hygiene & Tropical Medicine (LSHTM), University of Sheffield and Imperial College
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Betacoronaviruses have caused several major pandemics of zoonotic disease over the last few decades, the latest being the coronavirus disease 2019 (COVID-19) pandemic. Many of these viruses are endemic among bats, making the surveillance of these mammalian viruses a must to understand and prevent the spillover of these pathogens into humans. A new preprint discusses
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In a recent study published in the American Journal of Obstetrics and Gynecology, researchers reported that gestational diabetes mellitus (GDM) and obesity were associated with severe coronavirus disease 2019 (COVID-19). Study: Gestational diabetes mellitus and COVID-19: results from the CRONOS study. Image Credit: Svetolk/Shutterstock Background Pregnancy has been considered a risk factor for a severe
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The third year of the coronavirus disease 2019 (COVID-19) pandemic has disclosed newer issues like continued long covid symptoms and growing costs – measured in terms of lives and livelihoods lost (for example – education, mental health, and economies). Hence, global strategies to counteract future pandemics are warranted. Study: Inducing broad-based immunity against viruses with
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Thought LeadersAnand Patel and Michael Dyer Pediatric Oncologist and Developmental BiologistSt. Jude Children’s Hospital In this interview, News-Medical speaks to Anand Patel and Michael Dyer from St. Jude’s Children’s Research Hospital about their recent research suggesting EGFR inhibitors may prevent rhabdomyosarcoma recurrence. Please can you introduce yourself, tell us about your scientific background, and what inspired your latest research? Anand Patel: I
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Surveillance remains a critical strategy for reducing the impacts of coronavirus disease 2019 (COVID-19) while the transmission of severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2) continues, vaccination efforts are ongoing, and communities reopen. Study: Routine Saliva Testing for SARS-CoV-2 in Children: Partnering with Childcare Centers in the Greater New Haven Community. Image Credit: 24K-Production/Shutterstock As
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Scientists have observed that every individual responds differently to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causal agent of the coronavirus disease 2019 (COVID-19) pandemic. The evolution of SARS-CoV-2 due to genomic mutations has resulted in several variants, and each variant manifests the disease differently. Some variants cause severe infection, whereas others cause asymptomatic,
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Scientists from the German Max Planck Gesellschaft found out that a characteristic signature of volatile molecules is found in the breath of sexually aroused people. The test subjects exhaled less isoprene and carbon dioxide, while the concentration of degradation products of certain neurotransmitters increased. Image Credit: Ionicon Analytik Ges.m.b.H.  Related Stories The breath analysis was carried
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The Josep Carreras Institute becomes part of the Cancer Proteome project, an international initiative for the study of malignant tumors. It has the support of the Spanish Ministry of Science and Innovation, whose Minister, Diana Morant, visited the Josep Carreras Institute on Thursday and announced a grant of one million euros to promote the project.
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In a recent study published in Diabetes, researchers assessed the direct and indirect effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on human pancreatic islets. Study: Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets. Image Credit: Kateryna Kon/Shutterstock The correlation between new-onset hyperglycemia diagnosis with coronavirus disease 2019 (COVID-19) infection has been
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Hundreds of millions of cases of coronavirus disease 2019 (COVID-19) have been documented over the last two years during the ongoing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With many of these being severe enough to merit hospitalization, it has been a focus of research to understand how individual patients can
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To prevent the further spread of coronavirus disease-19 (COVID-19) infection, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), most countries worldwide implemented travel restrictions. Researchers conducted epidemiologic and genomic studies to investigate in-flight SARS-CoV-2 infection associated with repatriation flights from India to Australia in April 2021. This study has been published as a research
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By using data representing 80% of the US population, researchers have found that increased vaccination coverage against coronavirus disease 2019 (COVID-19) can be linked to a reduced incidence of cases and deaths. The study was published in the British Medical Journal (BMJ) and is freely available. Study: Public health impact of covid-19 vaccines in the
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High-risk patients who need defibrillators to prevent cardiac arrest can experience fewer complications with a type of device implanted under the skin, a Canadian study has found. Traditional defibrillators, while highly effective, involve placing a wire through a vein, into the chest and into the heart itself. The wires, known as ‘leads,’ in the traditional
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Several nursing teams from Roswell Park Comprehensive Cancer Center were invited to share their research at the 47th Annual Congress of the Oncology Nursing Society (ONS), which is underway in Anaheim, California, and continues through May 1, 2022. Among the specialists discussing new developments and challenges in the practice of nursing at the ONS Annual
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Research led by King’s College London and South London and Maudsley NHS Foundation Trust has analyzed factors associated with self-harm in over 111,000 adolescents aged 11-17 years old. Published in BMC Medicine the study found that the risk for self-harm presenting to hospital emergency departments was nearly three times higher for boys with autism spectrum
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Cigarette smoke has been shown to deleteriously affect human health. For example, degenerative disc diseases are increasingly linked to cigarette smoking. Nearly 3% of the particle matter in cigarette smoke is hydroquinone (HQ). HQ exposure has been linked to increased apoptosis and oxidative stress of the immune cells. However, it is still unclear how cigarette smoke
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Diagnosing Alzheimer’s disease can be a complex and time-consuming process, requiring evaluations ranging from brain scans to cognitive and lab tests to reviews of medical history and symptoms. Simpler and faster ways to diagnose the disease are urgently needed. Now, researchers at Albert Einstein College of Medicine have been awarded a five-year, $4.2 million National
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The risk of major complications for people who donate a kidney via laparoscopic surgery is minimal. That is the conclusion of a 20-year Mayo Clinic study of more than 3,000 living kidney donors. Only 2.5% of patients in the study experienced major complications, and all recovered completely. “The results of this study are extremely reassuring
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Children of women who took antipsychotic medications late in their pregnancy did not demonstrate increased risk of neurodevelopmental disorders, according to findings published in JAMA Internal Medicine. Women who take these drugs are at risk for having children with neurodevelopmental problems, but it is due to other lifestyle and medical factors, not the drugs; so
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In a recently published article in the journal Cancer Cell, scientists have demonstrated the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in cancer patients residing in Austria and Italy. The study reveals an induction in Omicron breakthrough infections in patients with hematologic and solid cancers. Study: Enhanced SARS-CoV-2 breakthrough infections in patients
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