Allergies & Asthma

The FDA approved a pressured, metered-dose inhaler containing albuterol and budesonide (Airsupra) for treating adults with asthma, drugmaker AstraZeneca announced. The combination, formerly known as PT027, is specifically indicated for the as-needed treatment or prevention of bronchoconstriction and to reduce the risk of exacerbations in adults with asthma, and is the first product containing both
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While there was no association between prenatal exposure to acid-suppressive medications and allergic diseases in kids, infant exposure was linked to a higher risk of developing asthma, a South Korean nationwide cohort study showed. Among over 84,000 pairs of infants exposed and unexposed to proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs), the
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In this video, MedPage Today editor-in-chief Jeremy Faust, MD, sits down with allergist and immunologist Zachary Rubin, MD, of Oak Brook Allergists in Illinois, to discuss the lasting affects of COVID-19 on pediatric health. Part one of their discussion — where they discuss the pediatric “tripledemic” of flu, respiratory syncytial virus (RSV), and COVID-19 —
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Dupilumab (Dupixent) was superior to placebo in the phase III trial underpinning its approval last spring for eosinophilic esophagitis (EoE), researchers said. About 60% of patients receiving the active drug — a monoclonal antibody targeting interleukin (IL) types 4 and 13 — achieved histologic remission, compared with just 5%-6% assigned to placebo in the multi-part
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After suffering allergy season after allergy season, many people will offer their best piece of advice for managing your symptoms. One common recommendation is nasal sprays. This blog dives into how nasal sprays work, how they’re different than oral antihistamines, and how disease-modifying treatment can help reduce the need for symptom relievers over time. How
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Among patients with chronic obstructive pulmonary disease (COPD) and severe chronic breathlessness, short-term daily treatment with low doses of extended-release morphine did not significantly reduce the intensity of worst breathlessness, a randomized trial showed. At 1 week, change in the intensity of worst breathlessness was not significantly different between patients who received 8 mg/day of
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LOUISVILLE, Ky. — An investigational fixed-dose combination of a short-acting beta2-adrenergic agonist and an inhaled corticosteroid appeared to slow the deterioration in lung function and reduce severe exacerbations for patients with mild-to-moderate asthma, according to an exploratory analysis of a phase III trial. Among the nearly 1,000 patients in the DENALI trial, those in the
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LOUISVILLE, Ky. — A sublingual film may be able to deliver epinephrine as effectively as intramuscular injections and provide an alternate pathway for urgent treatment of allergic anaphylaxis, a researcher suggested here. In testing with healthy volunteers, the sublingual film loaded with AQST-109, which delivers 12 mg of epinephrine, appeared to have similar pharmacokinetics as
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LOUISVILLE, Ky. — Treatment with add-on dupilumab (Dupixent) was linked with clinically meaningful improvements in hives and itch severity in patients with chronic spontaneous urticaria (CSU), according to the LIBERTY-CSU CUPID Study A trial. In patients as young as 6 years with itch and hives that were not adequately controlled on antihistamine treatment alone, dupilumab
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LOUISVILLE, Ky. — An accelerated form of intradermal skin testing (IDT) was found feasible and safe in patients with suspected allergies to hymenoptera venom, such as those from bee and wasp stings, researchers stated. In a retrospective study comparing adverse events (AEs) in patients who underwent standard and accelerated flying hymenoptera venom IDT, none of
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For the most part, everyone knows the feeling of being tired. Sleep deprivation is a serious issue that can lead to health complications like weight gain, weakened immunity, irritability, and even heart disease. Allergies and their corresponding symptoms such as coughing, sneezing, headaches, and nasal congestion can cause someone to lose hours of valuable sleep.
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The FDA’s Pulmonary-Allergy Drugs Advisory Committee on Tuesday will consider whether a novel two-drug combination inhaler for asthma should be the first FDA-approved product containing an inhaled corticosteroid (budesonide) and a short-acting beta2-adrenergic agonist (albuterol sulfate). Also novel is the proposed indication of preventing severe exacerbations, and the use of an inhaled corticosteroid-containing product as
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Millions of Americans suffer from spring and fall allergies every year. Many haven’t considered the area they live in and how it contributes to their allergy symptoms. The AAFA’s yearly Allergy Capitals™ report identifies which cities are the most challenging to live in with seasonal allergies. The report considers these factors: Spring pollen scores Fall
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